If you are using this medication at home, learn all preparation and usage instructions from your health care professional. However, side effects at the 150 mg dose may indicate that you might not . If you have symptoms of a low phosphorus level, call your doctor. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. You may need extra iron because of blood loss during kidney dialysis. On day three I had a headache and felt heavy/exhausted, which lasted a few days. wAd**CgI%"nn{Oa[q{r5 The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. TheNational Instituteof Health (NIH) and the U.S.Food and Drug Administration(FDA) monitor the side effectsof new and approved medications to ensure safety. There may be risks to the mother and fetus associated with untreated IDA in pregnancy. Low iron saturation, or iron deficiency, has various possible causes. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. taste impairment. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. It belongs to a class of medications called iron replacement products. Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. There are 2 tests that your doctor will likely This site is intended for use only by US patients. Any long-term side effects/dangers from iron infusions? Do not share your drugs with others and do not take anyone else's drugs. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. Diarrhea is a common side effect of most iron replacement products, which is the group of drugs that Injectafer belongs to. %PDF-1.3 Its not known if Injectafer is safe to take during pregnancy. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. However, diarrhea it isnt very common in people using Injectafer. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Details. (IV iron is absorbed by the body more rapidly than oral iron.) In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. Seriousside effectsshould be reported to a physician and/orPharmDfor medical advice. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. If you notice other effects not listed above, contact your doctor or pharmacist. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction. This may lead to the person needing a higher dose compared to someone who is muchsmaller. Venofer may reduce the absorption of iron preparations taken by mouth. With slow IV injection, the drug is given as a single, slow injection into your vein. Theyll do this by checking certain blood tests. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. No, Injectafer itself wont make you gain weight. Why is the range so wide? When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Venofer also comes as a liquid thats given by either IV infusion or a slow IV injection. VenAccess is a trademark of Vifor (International) Inc. Switzerland. This is why family members often have the same issues with drugs as others in theirfamily. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. People in the study received treatment with either Injectafer or Venofer. Call your doctor right away if youre having a severe allergic reaction to Injectafer, even if youve had doses of the drug in the past without any problems. Injectafer comes as a liquid solution inside vials. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. They can tell you about other medications that may work well for you. Symptoms include shock, dangerously low blood pressure, loss of consciousness, and/or collapse. Its because everyones body is different. Before using, check this product visually for particles or discoloration. generalized weakness. pain in the arms or legs. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. However, consuming large amounts of alcohol can actually cause anemia in some people. Copyright 1996-2023 Cerner Multum, Inc. Review our medical disclaimer. reactions at the site of the injection. This medication is given by injection into a vein as directed by your doctor. This is not a complete list of side effects and others may occur. With IV infusion, the drug is given as a slow drip into your vein over a period of time. Keep all drugs out of the reach of children and pets. Theyll recommend how to manage your condition. You will need frequent medical tests to help your doctor determine how long to treat you with Venofer. Patients with celiac disease (gluten intolerance). After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Youll receive doses of Injectafer from a healthcare professional at a medical facility. Very bad and sometimes deadly allergic side effects have rarely happened. If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. I had my first infusion of 1gm 10 days ago. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. But you likely wont feel the drug working inside of you. If you think there has been an overdose, call your poison control center or get medical care right away. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. They can give you tips on how to deal with any side effects that may be bothersome. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. Call your doctor for medical advice about side effects. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Injectafer is available only as a brand-name medication. Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. And this type of reaction is possible even if you didnt have a reaction to your first dose of the drug. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Venofer injection contains iron sucrose, a form of the mineral iron. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. Youll receive doses of either drug by a healthcare professional at a medical facility. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Cardiovascular health: Insomnia linked to greater risk of heart attack. Generics tend to cost less than brand-name drugs. Venofer is for use in adults and children at least 2 years old. So theres no recommended pediatric dosage for Injectafer. Their medical staff can help you set up another time to receive your Injectafer dose. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. But you dont necessarily need to eat these foods unless your doctor tells you to do so. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. This is not a list of all drugs or health problems that interact with this medicine. Depending on your anemia symptoms, your weight changes may be different than those described here. Learn how to store and discard medical supplies safely. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. As with most drugs, some people can have an allergic reaction after taking Injectafer. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Once inside your body, ferric carboxymaltose releases iron into your system. 12 Medicines That Could Help, List Venofer Vial side effects by likelihood and severity. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. Consult your pharmacist or local waste disposal company. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. Below are examples of these side effects. Last reviewed . Ask your doctor or healthcare provider if Venofer is the right choice for you. Call your doctor for medical advice about side effects. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. What to Expect When You Get Your Whole Genome Sequenced, DNA Data Can Help You Understand Ehlers-Danlos Syndrome (EDS). Innovators Monograph Iron infusions are given directly into a vein. Cancer patients who have anemia and are taking an ESA. This includes your doctors, nurses, pharmacists, and dentists. Dilute Venofer in a maximum of 250 mL of 0.9% NaCl. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Keep out of reach of children. One of the most commonly used tests to monitor IDA is the hemoglobin test. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Most people will metabolize medication by half every time it circulates the body. For some people, it may be OK to continue taking a multivitamin that contains iron. For reasons we dont fully understand, some peoples immune system gets over-activated when the drug enters their body. These lists dont include all possible side effects. This hormone is made by your kidneys. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. There are currently no generic forms of either drug. stream But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. Your doctor will do laboratory tests to monitor your response. This website is intended for use by US healthcare professionals only. However, since peoples bodies react so differently to drugs, they often have to change their stance on certaindrugs. All patients receiving Venofer require periodic blood tests to monitor the amount of iron in the blood. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Injectafer contains the active drug ferric carboxymaltose, while Feraheme contains the active drug ferumoxytol. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. Best food forward: Are algae the future of sustainable nutrition? With slow IV injection, the drug is given as a single, slow injection into your vein. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. Brand-name medications usually cost more than generics. Side effectswill last a very long time if the cause of them is not resolved. Serious side effects should be reported to a physician and/or PharmD for medical advice. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Have blood work checked as you have been told by the doctor. The information provided is not intended to replace your healthcare provider's medical advice. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Do not flush down a toilet or pour down a drain unless you are told to do so. These side effects may include constipation and diarrhea. All rights reserved. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. dizziness. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. Mental healthdisorders like depression may requireantidepressantsto treat. Iron sucrose can also be mixed in a. Terminal half-life ranges from 7 to 12 hours. 1 0 obj Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; fever. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. Find out what health conditions may be a health risk when taken with Venofer Vial xmq92\Kz!yIP}2~(?c/JUCK2~o_N=>K$o/_7'Z+nRkKM^y{u|ZFh$v}]O~vfo=.GowGFodVj-[-~x]Kg~9H'%h={OX/#S|Mc~|]_2nv`wwotn/+$G[{hGrP}sbZG-RGf#l~~l|Qnccml_iPy]G\17c,yPF[28z&I'+B(?rrvi,G?}/;'?;pm>?.i42ONmk~ai_u0z9o_? I had Venofer infusions, 2 rounds now in the span of three years. Side effects like nausea and low blood pressure are common with most iron infusions. In this study, compared with their level before treatment: Injectafer isnt currently approved for use in children. Its caused by your body not having enough iron, which is needed to make hemoglobin. You may also need to monitor your blood pressure at home. Call your doctor for medical advice about side effects. For people with certain medical implants, such as pacemakers, an MRI may pose an . Injectafer contains the active drug ferric carboxymaltose. Side effectsare uncomfortable reactions to medications or drugs. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). And the drug has also been studied in children with IDA who have inflammatory bowel disease (IBD). In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. The Injectafer dosage your doctor prescribes will depend on your body weight. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. Also tell them about any vitamins, herbs, and supplements you use. Keep all drugs in a safe place. This is why the FDA hasa programcalledMedWatchthat encourages Americans to report adversereactions. Venofer is used to treat iron deficiency anemia in people with kidney disease. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. Its not known if Injectafer is safe to use during pregnancy. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. Examples of thisinclude: Not allside effectslast forever. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. muscle pain. Talk with the doctor. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. If youre wondering how longside effectslast, youll be happy to know they can last just a few hours. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Suffering from somemedical conditionsput people at risk fordrugside effectsof medications for other health concerns. And theyll recommend how soon after starting the drug you need to have this level checked. Do not start, stop, or change the dose of any drug without checking with your doctor. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. Together, they can recommend ways to help you manage a body weight thats healthy for you. You should always consult your doctor or another healthcare professional before taking any medication. You may report side effects to the FDA at 1-800-332-1088. Spacing your Injectafer doses out at least 7 days helps to reduce your risk of side effects. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. Headache. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Can poor sleep impact your weight loss goals? administered at your doctors office or an infusion center. Do not exceed 1,500 mg of iron per dosing course. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. And this can lead to anemia, including IDA. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. In the US - Call your doctor for medical advice about side effects. Evenbirth controlcan lead to severeside effectslike bloodclots. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. The Role of Genetics in Multifactorial Disorders, The Power of DNA Testing and Predictive Medicine, A Guide to Genome Explorer (Free Version), Whole Genome Sequencing in As Little As Three Weeks, What Diseases Can Be Detected Through Genetic Testing, Breast Cancer Genetic Testing: Pros and Cons, At Home Genetic Testing for Breast Cancer, DNA Tests for Breast Cancer Genetic Testing, What to Do When Medicines Have Side Effects, Blood Type and COVID: Infection Risk and Severity, Where Can I Get My Blood Type Checked for Free, How to Find Biological Father Through DNA. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. Here we look at how Injectafer and Feraheme are alike and different. Brand-name medications usually cost more than generics. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. treatment schedule in further detail. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). Use Venofer as ordered by your doctor. In the first group, some people continued taking iron by mouth, while other people took Injectafer. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. Dr. Colby is alsothe Founder of Sequencing.com and the authorofOutsmart Your Genes. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. It depends. Grapefruitjuice may be healthy for people to drink, but it can cause someseriousside effects. Its not known whether its safe to breastfeed while youre taking Injectafer. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. But for other people, doing so could lead to having too much iron in their body. In clinical trials,. But some people have a delayed allergic reaction to certain drugs. US residents can call their local poison control center at 1-800-222-1222. Tell your doctor if you are taking iron supplements or other iron-based oral medications. You may report side effects to FDA at 1-800-FDA-1088. Side effects are uncomfortable reactions to medications or drugs. A lack of iron can lead to iron deficiency anaemia if left untreated. This medicine is used to treat "iron-poor" blood (anemia) in people with long-term kidney disease. Drug class: Iron products. Read all information given to you. Injectafer isnt a medication that youll take regularly on a schedule. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Vomiting. . I was surprised too but the Dr said it definitely sounds like a reaction. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. Check with your pharmacist. (A class of medications describes a group of drugs that work in the same way.). fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This gives a total cumulative dose of 1,500 mg of Injectafer. Its responsible for carrying oxygen throughout your body. But its not known whether this poses any risk to a child whos breastfed. weakness.
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